CB1 Receptor Chart

The Endocannabinoid System Explained

Introducing our CBD Literacy video education series

Ever wondered about the science behind CBD and its effects on your dog’s body? We know that many of our furry companions who use C.H.O.™ CBD Oil get relief from pain, anxiety, seizures and more. But you may have wondered, “how and why does CBD work?”

Our friend and colleague Sam Stewart, DVM, from Ethos Veterinary Health, has prepared this excellent video to explain the endocannibinoid system. This video is the first in a series–part of our effort to lead the way in veterinary CBD research and education. In this first video, you’ll gain a better understanding of how cannabinoids like CBD affect the brain and nervous system. About halfway through (10:22), Sam gives a great example of how CBD interrupts pain signals in the peripheral nervous system. And at minute 17, you’ll find a great explanation of how CBD binds to receptors and inhibits inflammation. The entire video provides a great overview–in layman’s terms–of the powerful endocannabinoid system.

At ABSC, we’re constantly working to improve and evolve science in the name of providing a better quality of life for our ailing companion animals. Want to learn more? Check out our News and Research Library! And subscribe to our YouTube channel–we’ve got more great educational content to come!

Applied Basic Science tests every batch of C.H.O.™ Pet CBD Oil.

Pure CBD oil Eliminates Contaminants

Contaminants can jeopardize recovery

In “Pet Owners Turn to CBD to Treat Animals,” NBC Miami journalist Dan Krauth highlights an important side of testing when it comes to CBD products. You want to know what’s in your pet’s CBD oil. But it’s equally important to know what’s not in the products you buy. Not every product on the market is safe; some CBD oils have tested positive for mold and other contaminants. And that’s a big problem says Chris Martinez. Martinez runs a lab that performs independent testing for more than 400 companies.

“It’s definitely something to be concerned about from this point forward,” said Martinez. “A microbial can be a life-threatening situation for a patient or a dog that’s suffering from some type of immune deficiency disease.”

Krauth, Dan. “Pet Owners Turn to CBD to Treat Animals.” NBC Miami, NBC Universal Media, 6 Feb. 2019, https://www.nbcmiami.com/investigations/Pet-Owners-Turn-to-CBD-to-Treat-Animals-505475071.html

Clean CBD is Good CBD

If you’ve been an Applied Basic Science customer for long, you probably already know that we test every batch of ABSC Pure Organic CBD Oil™ for CBD concentration consistency. Did you know that we also test for the presence of contaminants? With each batch, we look for pesticides, fungicides, microbial contaminants, and solvents. We know that many of our patients are dealing with difficult ailments, and we’re committed to making sure our CBD oil is pure and safe. Fungi and other contaminants can stress your pet’s immune system and complicate their recovery. That’s the last thing you want when your beloved pet is suffering.

Routinely testing our CBD oil for undesirable contaminants such as pesticides, microbial contaminants, and solvents is a cornerstone of our safety protocol.
Sample Certificate of Analysis from one of our batches.

Applied Basic Science Cares For Your Pet

Applied Basic Science cares for your pet with CBD oil that has gone through three clinical trials and rigorous batch testing. Whether you’re treating for osteoarthritis, anxiety, fungal infections, or seizures, you can rest easy when you buy ABSC Pure Organic CBD Oil™.

You deserve peace of mind. Get it at petpainfree.com. Our organic CBD oil is pure and safe for your furry family member.

Blastomycosis Beware – CBD as Complementray Therapy for Fungal Infections

CBD oil may help stave off Blastomycosis symptoms

Recently a valued customer reached out to us with an unusual story. We have hundreds of pet owners who give their dogs ABSC Pure Organic CBD Oil™ to help with osteoarthritis, seizures, and anxiety. We know our CBD oil routinely helps canine patients deal with cancer and the ravages of chemotherapy. And we know that some skin issues resolve with the addition of CBD oil. But Ashley Gaer’s story of her beloved Newfoundland Cass and his experience with Blastomycosis was something new.

Blastomycosis typically attacks male large breeds who spend a lot of time in the water.
Cass (brown) and his brother Elmore (black) both enjoy benefits from ABSC Pure Organic CBD Oil™.

What is Blastomycosis?

Blastomycosis is a systemic fungal infection caused by an organism that thrives in rotting wood and wet soil. Dogs that spend a lot of time in the water and in wet environments – especially male large breed hunting and sporting dogs –  are most susceptible to Blastomycosis infections.

Ashley’s dog Cass is a Newfoundland – clearly part of the susceptible population. Newfies are large breed working dogs who are most at home in the water. These gentle giants even have webbed paws, and they are known for their ability to perform dramatic rescues in icy waters.

How does a dog get Blastomycosis?

Most canines get Blastomycosis by inhaling the fungal spores. The spores travel through the dog’s respiratory system and become large yeast-like organisms that multiply throughout the body.

Cass was diagnosed with Blastomycosis in 2018. Ashley suspects that he inhaled the spores while doing water rescue work in an area where the fungus is prevalent.

What are the symptoms of Blastomycosis?

According to Dr. Karen Becker, symptoms include loss of appetite, fever, weight loss, inflammation of the iris of the eye, coughing, and pus-filled skin lesions. More severe symptoms can include sudden blindness, lameness, and seizures.

Cass’s presentation was a little different than most. His symptoms have included bone, muscle, and joint issues, coupled with respiratory complications that initially looked like kennel cough. Ashley feels strongly that using ABSC Pure Organic CBD Oil™ as a complementary therapy–along with prescribed anti-fungal medications–has allowed her Newfie to keep up his appetite and stamina. “I think it really has helped Cass,” she says, “because he has NEVER lost his appetite and frankly, any energy, during his fight with it. This is a sickness that kills dogs and he has only once had a flare up and even then, I had him on the 2400mg and he recovered in 24 hours.”

How is Blastomycosis typically treated?

The standard treatment for Blastomycosis infections is a long course of anti-fungal medications. Some dogs may stay on the meds for many months as they battle the fungus, and marked weight loss often occurs. Ashley says the anti-fungals were rough on Cass’s system, but stresses the importance of sticking with the medications for their entire prescribed course. She credits the CBD oil with easing the side effects and allowing Cass to stay strong throughout the treatment.

We’re thrilled that our ABSC Pure Organic CBD Oil™ is helping Cass fight off his fungal foe, and so grateful to Ashley for telling us his story. Want to learn more about Blastomycosis? Check out Dr. Becker’s informative article here. And read Ashley’s testimonial for more great information about Cass and his brother Elmore.

Huge thanks to Ashley and her beautiful boys. Have you got a story to share? We always love hearing from customers–email us!

Applied Basic Science Shines at 20th Annual CVMBS Research Day

Research students at Colorado State University – working with CBD oil supplied by Applied Basic Science – garnered third place accolades at the 20th Annual CVMBS Research Day on Saturday. This informative poster details a current canine epilepsy study conducted by Dr. Stephanie McGrath at CSU. Dr. McGrath and her team are working in conjunction with Applied Basic Science and the American Kennel Club – Canine Health Foundation. Their current study tests the following hypothesis: CBD will be a safe and effective therapy for uncontrolled canine epilepsy with minimal adverse side effects. Promising preliminary results are encouraging. Researchers note that “CBD has the potential to reduce seizure frequency in dogs with uncontrolled, idiopathic epilepsy.”

CBD Oil provided by Applied Basic Science shows promising results with canine epilepsy patients.
CBD research

Clinical Testing Defines Applied Basic Science

CBD—the non-psychoactive derivative of the marijuana and hemp plants—has taken off among humans, marketed as a solution for everything from pain and anxiety to skin care and diet.

CBD Safetly Trial CSU

Groundbreaking Safety, Toxicity, and Pharmacokinetics Study Published

ABSC Sponsored Safety Study Published in the  Journal of the American Holistic Veterinary Medical Association

We are thrilled to announce that our Phase 1 Clinical Trial: Assessment of Safety, Toxicity, and Pharmacokinetics of Cannabidiol in Healthy Dogs has been successfully completed. Sponsored by ABSC Organics and conducted at Colorado State University’s College of Veterinary Medicine and Biomedical Sciences, the trial studied three different delivery mechanisms in 30 healthy beagles. With results appearing in the Fall 2018 issue of the Journal of the American Holistic Veterinary Medical Association, the study concluded that clinical doses of CBD were well tolerated by all the dogs in the study. This is groundbreaking news in the veterinary field, and represents a major step forward for CBD research and pet wellness.

St. Bernard in CBD Clinical Trial
Dr. Stephanie McGrath with Atticus, a 3-year-old Saint Bernard enrolled in a clinical trial of cannabidiol at Colorado State University’s Veterinary Teaching Hospital (Photo by John Eisele/Colorado State University Photography)

ABSC Organics–The Only Veterinary CBD Company With a Phase 1 Safety Trial

At ABSC we know that it’s easy to make claims, but more important to invest in the research to back up those claims. We care deeply about pets and their well-being. That’s why we’re so proud of the fact that ABSC Pure Organic CBD Oil is the only veterinary CBD product that has undergone a Phase 1 trial to assess safety and toxicity. This trial enables researchers to use our product in Phase 2 trials that will study CBD’s effects on epilepsy, arthritis, and more.

AHVMA Logo

Two Clinical Studies: Osteoarthritis and Epilepsy

ABSC Pure Organic CBD Oil™ For Dogs Used in More Clinical Trials

Aided in large part by the commitment and investment of science-driven firms like ABSC Organics, cannabis research for veterinary patients is cautiously advancing. Dr. Stephanie McGrath, a neurologist and assistant professor at Colorado State University’s College of Veterinary Medicine & Biomedical Sciences, is on the forefront of veterinary cannabidiol research. She has completed two recent clinical studies on the effects of cannabidiol in dogs with epilepsy or osteoarthritis. This work was recently published in The Journal of the American Veterinary Association:

“An initial investigation involving 30 healthy research animals found that CBD was tolerated and resulted in measurable blood concentrations. Dr. McGrath expects results of that study will be published this year. Data from the other studies are being analyzed, but preliminary results of the epilepsy investigation were promising enough that, in January, Dr. McGrath began a three-year crossover study of CBD for epilepsy in dogs with a $350,000 grant from the American Kennel Club.”

ABSC Organics is a Proud Partner in Advancing the Field of Veterinary CBD Research

ABSC Organics provided the funding and CBD oil for Dr. McGrath’s study. We are deeply committed to raising the bar for research and analysis in this arena, and we are proud to partner with the scientists who are leading the push for better data and rigorous clinical analysis.

For the full text of the JAVMA article, click here, or visit our News and Research page for news and updates on other ongoing clinical studies.

ABSC tests every batch of CBD oil for consistency and purity.

Penn Medicine Research Finds Mislabeled CBD Products

Rigorous Testing Ensures ABSC Pure Organic CBD Oil™ is consistent and pure.

In a 2017 study, Penn Medicine researcher Marcel Bonn-Miller, PhD, found that almost 70 percent of CBD products sold online are mislabeled. With extremely variable cannabidiol amounts, these products cause concern for researchers and medical professionals:

While studies have not shown that too much CBD can be harmful, products containing either too little or too much CBD than labeled could negate potential clinical benefit to patients. Further, the variability across products may make it troublesome for patients to get a reliable effect.
“People are using this as medicine for many conditions (anxiety, inflammation, pain, epilepsy),” Bonn-Miller explained. “The biggest implication is that many of these patients may not be getting the proper dosage; they’re either not getting enough for it to be effective or they’re getting too much.”

“Penn Study Shows Nearly 70 Percent of Cannabidiol Extracts Sold Online Are Mislabeled.” Penn Medicine News, The Trustees of the University of Pennsylvania, 7 Nov. 2017, https://www.pennmedicine.org/news/news-releases/2017/november/penn-study-shows-nearly-70-percent-of-cannabidiol-extracts-sold-online-are-mislabeled

Applied Basic Science is the Leader in Testing & Trials

Your pet deserves the safest CBD oil on the market. We test our C.H.O.™ Pet Tincture rigorously to ensure accurate labeling and dosage.
Pets are family. Give them the best.

At Applied Basic Science, we know that our customers need accurate labeling and specific dosage instructions. You need to know that you are administering the right amount of CBD for your pet. That’s why we test each batch for each CBD and THC levels. (The Penn Medicine study also found many products contained “a significant amount of THC.”) And our testing doesn’t stop there – we also test for the presence of unwanted contaminants. We do this to ensure that we’re always delivering a consistent and pure CBD product.

We know that your pets are part of your family. Our commitment to research and testing lets you buy confidently, knowing you are getting the best veterinary CBD product on the market. Your peace of mind is our peace of mind. Thanks for trusting us!

CBD clinical studies

CBD-Infused Oil Delivers the Goods

The July 2018 issue of the Canadian Journal of Veterinary Medicine highlights a clinical study investigating CBD delivery methods. Dr. McGrath and her colleagues looked at how…

C.H.O Pet Tincture

“Promising” News for CBD Epilepsy Treatment

ABSC Pure Organic CBD Oil Used in Pilot Epilepsy Study at Colorado State University

Great news out of Dr. McGrath’s lab at Colorado State University! Dr. McGrath–a veterinary neurologist at the University’s James L. Voss Teaching Hospital–conducted a double-blind pilot study using ABSC Pure Organic CBD Oil to look at using CBD to treat dogs with epilepsy. Calling her preliminary results “very promising,” Dr. McGrath reports that 89% of the dogs in the small pilot study showed a reduction in seizure frequency.

Sixteen dogs were enrolled in the clinical trial. Nine dogs were treated with CBD, which has 0.3 percent or less of the psychoactive component of cannabis, THC; seven dogs in a control group were treated with a placebo. The compound is not considered marijuana and can be used for research purposes based on the 2014 United States Department of Agriculture Farm Bill.

Giuden, Mary. July 19, 2019. Preliminary data from CBD clinical trials ‘promising.’ News from the College of Veterinary Medicine and Biomedical Sciences. https://cvmbs.source.colostate.edu/preliminary-data-from-cbd-clinical-trials-promising/

We Care Enough To Do the Research

We are thrilled to be part of Dr. McGrath’s research, and to see these encouraging results with canine epilepsy patients. Although we have many anecdotal stories about CBD’s ability to reduce the frequency and severity of seizures, it’s important that we continue to gather clinical research and evidence. That’s why we will always support researchers like Dr. McGrath, who are leading the charge for more knowledge about CBD.

More Clinical Trials

Dr. McGrath and her colleagues at Colorado State have launched a larger clinical trial for epilepsy, and are seeking to enroll 60 dogs. You can learn more about that trial, including how to enroll, at the teaching hospital’s website. Want to learn more about other clinical trials happening with ABSC Pure Organic CBD Oil? You can visit our News & Research page for updates on all the exciting things happening with veterinary CBD research!

Encouraging News for Veterinary CBD Oil Use

Dr. Karen Becker of Mercola Healthy Pets profiles the CSU clinical trials and discusses encouraging progress in the CBD industry in “The Effective Pain Treatment Your Vet May Not Want to Talk About.”

In the article, Dr. Becker discusses the changing legal landscape for CBD products, noting that industrial hemp – with a THC level under 0.3 percent – is no longer considered a controlled substance. Current research suggests that manufacturing and distributing CBD oil for veterinary use is not illegal on either a federal or state level.

Becker also details the ongoing research happening at Colorado State University Veterinary Teaching Hospital and Cornell University College of Veterinary Medicine. At Colorado State, Dr. Stephanie McGrath, who specializes in treating seizure disorders and inflammatory brain diseases in animals, is using ABSC Pure Organic CBD Oil™ in her osteoarthritis and epilepsy study:

“Dr. McGrath at Colorado State used a CBD product manufactured by Applied Basic Science Corporation, and vouches for its safety. She also recommends, if you’re already using a CBD product or are considering one, that you try to get a “Certificate of Analysis” which should show you how much THC is in the product (it should never be over 0.3 percent), how it’s made, and whether it’s organic and free of pesticides and other chemicals.”

We’re proud to partner with Dr. McGrath in support of the clinical trials that enable us to sell our product with confidence, and we’re committed to ongoing safety testing. Every batch of ABSC Pure Organic CBD Oil™ For Pets undergoes quality testing and receives a Certificate of Analysis (COA) from a third party lab. And we’re happy to share our results – click here to view our most recent COA. At petpainfree.com, you can buy with confidence knowing we back our product with the highest standards of testing and accountability.